2017-04-24 15:34:122025-05-22 07:10:28
description
two-component response regulator (OmpR family), regulation of aerobic and anaerobic respiration, activates expression of target genes in response to oxygen limitation
two-component response regulator ([SW|OmpR family]), regulation of aerobic and anaerobic respiration, activates expression of target genes in response to oxygen limitation
locus
BSU23120
BSU_23120
geneLength
720
723
function
regulation of aerobic and anaerobic respiration respiration
regulation of aerobic and anaerobic respiration
product
two-component response regulator (OmpR family)
two-component response regulator ([SW|OmpR family])
ec
outlinks
bsu
BSU23120
BSU_23120
Gene
Coordinates
2,417,181 → 2,417,903
2,417,181 2,417,903
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cytoplasm (according to Swiss-Prot)
Labs working on this gene/protein
[SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]
References
Original publications
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|Response regulatory domain] (aa 8-121) (according to UniProt)
The protein
Structure
[PDB|2OQR] (RegX3 from Mycobacterium tuberculosis, 37% identity) [pubmed|17942407]
The protein
additional information
[[protein|ResD]] may interact with [SW|RNA polymerase] [pubmed|21710567]
information on binding sites can be found in the [http://www.prodoric2.de/detail.php?acc=MX000009 PRODORIC2 database]
Biological materials
Mutant
BKE23120 ([[gene|resD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTCCCCCTGCTTTC, downstream forward: _UP4_TATAAATTTGAGGTCGGCGC
BKK23120 ([[gene|resD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTCCCCCTGCTTTC, downstream forward: _UP4_TATAAATTTGAGGTCGGCGC
labs
[SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]